Omics

Within the EnvironMENTAL project, the IMAGEN cohort was enriched with newly acquired multi-omics data, strengthening the investigation of biological mechanisms linking environmental adversity to brain and behavioural outcomes.

 

DNA Methylation
Acquisition centre: Life & Brain (L&B)
Epigenetic profiling to identify environmentally sensitive biological signatures.

 

RNA Sequencing
Acquisition & analysis centre: Universitätsklinikum Bonn (UKB)
Gene expression profiling to assess how genes are regulated in relation to environmental exposures.

 

Proteomics
Acquisition centre: Charité, Universitätsmedizin Berlin
Large-scale protein profiling to characterise systemic biological pathways linked to mental health risk.